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  • Author: Yvonne Coleman

November 30, 2021

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Iron supplements and gut microbiota

Mechanisms and outcomesIron supplements are generally prescribed if serum iron levels are low. Poorly absorbed iron, typically from sources such ...

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November 25, 2021

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Potential pharmaconutrition research topics 3

Potential research topicsNutrition research, including pharmaconutrition, is an interesting and challenging field, with an added dimension that is not essential ...

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November 16, 2021

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Riboflavin and some TCAs and phenothiazines

Mechanisms and outcomesBecause chlorpromazine (a phenothiazine), imipramine (a tricyclic acid) and amitriptyline (a tricyclic acid) have very similar structures to ...

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November 9, 2021

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Methotrexate and folate – pharmaconutrition implications

Mechanisms and outcomesMethotrexate is both an antagonist and an analogue of folic acid ie it is a nutrient-derivative drug. Methotrexate ...

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November 1, 2021

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What do physiological transporters have in common with bus services?

Mechanisms and consequencesWhat do physiological transporters aka drug transporters and bus services have in common?Networks, hubs, defined load capacities and ...

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October 26, 2021

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Potential pharmaconutrition research topics 2

Potential research topicsIn the early 1990s a Canadian research team was investigating whether alcohol interacted with nifedipine/felodipine and unexpectedly found ...

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October 19, 2021

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Drug-food interactions advice

Mechanisms and consequencesDrug-food interaction advice is quite inconsistent and falls into three main groups – advice not provided, food contra-indicated, ...

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October 12, 2021

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Pharmaconutrition – costs and benefits

Mechanisms and consequencesConfusion, falls or has poor balance, insomnia, and lethargy - would you immediately be trying to decide if ...

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October 5, 2021

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B12 injection

Mechanisms and outcomesAbnormally high B12 levels are typically due to a medical disorder, however this article is specifically about elevated ...

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September 28, 2021

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Potential pharmaconutrition research topics 1

Potential research topicsTwenty years ago, this was a very short list! Of necessity this list has grown as there has ...

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September 21, 2021

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The daily double – metformin and proton pump inhibitors (PPI)

Mechanisms and consequencesMetformin and proton pump inhibitors both decease vitamin B12 absorption, and decrease thiamine availability.Metformin is the fourth most ...

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September 14, 2021

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Drug-food interactions

Mechanisms and consequencesMaximising drug dose or minimising side effects were the only interactions that pharmaceutical companies considered in relation to ...

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September 7, 2021

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The trifecta – proton pump inhibitor, frusemide & digoxin

Mechanisms and consequencesThis trifecta has been prescribed since admission and likely before then; in this instance the trifecta refers to ...

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August 31, 2021

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Prednisolone, diabetes drugs and BSLs

Mechanisms and consequencesCommonly the pre-breakfast BSLs may be the only routine monitoring strategy for those with long term diabetes and ...

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August 24, 2021

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Medication Advisory Committees and pharmaconutrition

Mechanisms and consequencesMedication Advisory Committees (MACs) are an ideal forum for addressing a range of issues that have a medication:nutrition ...

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August 17, 2021

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Iron supplements – the bad and the ugly

Mechanisms and consequencesIron supplements are generally prescribed if serum iron levels are low and there is rarely any further intervention ...

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August 10, 2021

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Toxic metals and drug transporters – is there a concern?

Mechanisms and consequencesMembrane transportersMembrane transporters are euphemistically called “drug transporters” however their primary role is to move physiological substances to ...

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August 3, 2021

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Research numbers vs case numbers

Welcome!Welcome to the first edition of our weekly email - and thank you for your interest in pharmaconutrition.The content format ...

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