Drug-Food Interactions
An Overlooked Link Between Medicine and Nutrition
Interactions between prescribed medicines and foodstuffs can profoundly influence the effectiveness and safety of prescribed medicines. Individual drug-food interactions can be either/and complex and variable.
Typically, medicines are administered before meals to maximise therapeutic effects and with meals to reduce side effects. However, advice regarding interactions between prescribed medicines and food remains inconsistent and often confusing for both clinicians and patients.
Common Categories of Drug-Food Advice
Drug-food interaction guidance generally falls into three categories as outline.
No advice provided
Typically applies to very common foodstuffs such as caffeine;
Food contra-indicated
Examples include grapefruit and alcohol, both of which can alter drug metabolism.
Advice yet to be determined
As yet unidentified interactions – likely because any associated reactions are more likely to be attributed to the disease process rather than the treatment process.
Medications & Nutrition Platform
The Medications & Nutrition online platform provides referenced evidence of interactions between prescribed medicines and foodstuffs, focussing primarily on alcohol, caffeine and grapefruit. The information is presented in clear dot-point summaries to enable quick access.
Mechanisms and consequences Warfarin-vitamin K interactions are well-known warfarin-food interactions and so those prescribed warfarin are typically “educated” about vitamin ...
Mechanisms and consequences Caffeine is a commonly consumed foodstuff, typically found in beverages such as coffee, tea, cola, energy drinks, ...
Mechanisms and consequences Drug-food interaction advice is quite inconsistent and falls into three main groups – advice not provided, food ...
Mechanisms and consequences Maximising drug dose or minimising side effects were the only interactions that pharmaceutical companies considered in relation ...