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Drug-Food Interactions

An Overlooked Link Between Medicine and Nutrition

Interactions between prescribed medicines and foodstuffs can profoundly influence the effectiveness and safety of prescribed medicines. Individual drug-food interactions can be either/and complex and variable. Typically, medicines are administered before meals to maximise therapeutic effects and with meals to reduce side effects. However, advice regarding interactions between prescribed medicines and food remains inconsistent and often confusing for both clinicians and patients.

Common Categories of Drug-Food Advice

Drug-food interaction guidance generally falls into three categories as outline.

 No advice provided

Typically applies to very common foodstuffs such as caffeine;

Food contra-indicated

Examples include grapefruit and alcohol, both of which can alter drug metabolism.

Advice yet to be determined

As yet unidentified interactions – likely because any associated reactions are more likely to be attributed to the disease process rather than the treatment process.

Medications & Nutrition Platform

The Medications & Nutrition online platform provides referenced evidence of interactions between prescribed medicines and foodstuffs, focussing primarily on alcohol, caffeine and grapefruit. The information is presented in clear dot-point summaries to enable quick access.

November 28, 2022

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Warfarin-food interactions

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July 6, 2022

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Caffeine and pharmaconutrition

Mechanisms and consequences  Caffeine is a commonly consumed foodstuff, typically found in beverages such as coffee, tea, cola, energy drinks, ...

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Drug-food interactions advice

Mechanisms and consequences  Drug-food interaction advice is quite inconsistent and falls into three main groups – advice not provided, food ...

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September 14, 2021

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Drug-food interactions

Mechanisms and consequences  Maximising drug dose or minimising side effects were the only interactions that pharmaceutical companies considered in relation ...

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