DOACs (direct oral anticoagulants) are becoming the preferred option for coagulation management because they do not require the management strategies ...
December 5, 2022
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PharmacoNutrition
The interface between prescribed medicines and nutritional factors is so overlooked that it is commonly referred to as drug-nutrient interactions and/or drug-food interactions.Clinical category
PharmacoNutrition as a suitable name as it encompasses the broad scope of the field including both direct and indirect drug-food and drug-nutrient interactions. Those conducting research in this field would be Pharmaco-nutrologists.Primary contributors to clinical exclusion
Research aspects
Research papers are scattered across a plethora of journals and subjects. The studies are mostly small.Assumptions - for which there is no evidence
Food intake will cover the drug-induced nutrient losses. Food is benign and unlikely to interact with pharmaceuticals.Health professional training
The training for doctors, pharmacists, and most other health professionals does not include a significant nutrition component. This is surprising given 80+% of western ill-health has an underlying negative nutrition component.Who will fund and conduct the research?
Pharmaceutical industry
The regulatory processes do not require negative nutritional impacts of pharmaceutical products to be included in the drug discovery process.Governmental research bodies
The number of similarly worthwhile research projects competing for funding is steadily increasing whilst the funding sources and are generally not increasing.Philanthropic bodies
Philanthropic bodies either support a specific area of research or dispense smaller grants to a larger number of applicants. Sadly, there aren’t any philanthropic bodies with a particular interest in this area of expertise.Medications & Nutrition Platform
The online platform Medications & Nutrition provides a comprehensive range of clinically-useful, referenced, research evidence that is presented in a dot point format to improve accessibility to the latest research for busy clinicians. Examples of integration formats are included in the Case study component of our MedNut Mail series.November 7, 2022
Mechanisms and consequences Medications, medicines, drugs are used interchangeably to describe chemical substances that are administered to confer therapeutic benefit; ...
November 2, 2022
Acid-base imbalance is now being associated with a range of Western health disorders including insulin resistance, diabetes, thyroid function resistance, ...
October 24, 2022
Steady state concentration is the period during which the therapeutic levels remain constant. It is achieved when a defined amount ...
October 17, 2022
Mechanisms and consequences I now understand why duration of therapeutic effect of the non-insulin diabetes drugs is not an integral ...
October 10, 2022
Insulin resistance is defined as a lack of cellular response to insulin – likely due to closed, damaged or insufficient ...
October 4, 2022
Insulin is a highly effective anabolic hormone that is primarily produced in the pancreas, and small amounts are also produced ...
September 27, 2022
Mechanisms and consequences Supported by policies, practices and programs, harm minimisation is essentially a philosophy, in a range of sectors, ...
September 20, 2022
Mechanisms and consequences Denosumab is prescribed for the treatment of bone loss in adults at high risk of bone fractures. ...
September 15, 2022
Bone health is so important and so overlooked and is usually only considered once there is a problem. Mechanisms and ...
September 8, 2022
Guest case study A reader sent in this list of prescribed medications and did not provide any other information. Drug-food ...
July 25, 2022
Neuroinflammation occurs when the brain’s innate immune system is challenged by factors such as injury, infection, toxin exposure, or neurodegeneration, ...
July 19, 2022
Costs of inaction is a term typically associated with business decisions. What are the costs if you choose not to ...
July 12, 2022
Pantothenate is important in many basic physiological functions, and especially as a precursor for Coenzyme A also known as CoA ...
June 29, 2022
Mechanisms and consequences Astrocytes are overlooked essential intermediaries in neurological physiology. Astrocytes operate on a network system whereby they service ...
June 15, 2022
Mechanisms and consequences Pyridoxine (Vitamin B6) is important in many body functions and is seemingly now becoming “sexy” to some ...
June 8, 2022
Time-saving templates Templates are useful for ensuring essential information is passed on without any aspect being overlooked as they can ...
June 1, 2022
Pantothenate is a nutrient that is very out-of-sight and out-of-mind – is there, or should there be, a pharmaconutrition concern? ...
May 24, 2022
Mechanisms and consequences The combination of identification of physiological transporters and their potential for accessing currently inaccessible-for-pharmaceuticals parts of the ...
May 3, 2022
Mechanisms and consequences A recent seminal study (https://doi.org/10.1074/jbc.RA120.013610) found that ThTr1/2 (Thiamine Transporters 1/2) can transport both thiamine and pyridoxine ...
