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MedNut Mail - Our Medications & Nutrition Newsletter

Stay informed with MedNut Mail, a free weekly newsletter designed for busy clinicians and healthcare professionals who want to keep current on drug-nutrient interactions and pharmaconutrition research.

What is MedNut Mail?

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MedNut Mail delivers concise, evidence-based articles that explore the mechanisms, consequences, and clinical implications of drug-nutrient and drug-food interactions, grounded in recent scientific literature and expert insights.  

  • Typically published weekly with occasional bi-weekly in-depth articles.
  • Covers topics ranging from transporter proteins to effects of specific drugs like metformin on nutritional status.
  • Includes practical examples to integrate into clinical assessments.

Why subscribe?

  • Free and easy to use – no cost, no unnecessary emails.
  • Stay up to date with the latest research impacting clinical nutrition and medication management.
  • Practical clinical insights you can apply in your daily work.
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MedNut Mail archives

Explore past issues about medications and nutrition interactions available below. Sort by category or scroll down.

All
Distribution system
Drug-Food interactions
Drug-Nutrient interactions
PharmacoNutrition
Nutrient-nutrient interactions

Latest PharmacoNutrition posts

May 13, 2024

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Levodopa + carbidopa and iron interactions

Drug-Nutrient interactions

Mechanisms and consequences  Levodopa + carbidopa and iron interactions are both complex and extensive. ...

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April 23, 2024

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Drug-induced tipping points

PharmacoNutrition

Mechanisms and consequences  Drug-induced tipping points and health management strategies are an unlikely combination ...

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April 9, 2024

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Levodopa + carbidopa and thiamine

Drug-Nutrient interactions

Mechanisms and consequences  Levodopa + carbidopa and thiamine encompass a range of interactions that ...

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March 18, 2024

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Levodopa + carbidopa and vitamin C

Drug-Nutrient interactions

​Levodopa + carbidopa and vitamin C encompass a range of interactions that include both ...

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March 4, 2024

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Levodopa + carbidopa and Vitamin D

Drug-Nutrient interactions

​The levodopa + carbidopa and vitamin D interaction is apparently additive however the evidence ...

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February 19, 2024

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Levodopa + carbidopa and zinc interactions

Drug-Nutrient interactions

​Levodopa + carbidopa and zinc interactions are a surprisingly relatively recent finding. Mechanisms and ...

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February 5, 2024

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Levodopa + carbidopa and manganese

Drug-Nutrient interactions

Mechanisms and consequences  Is there evidence of a levodopa + carbidopa and manganese interaction?  ...

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January 29, 2024

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Levodopa + carbidopa, magnesium and vitamin C

Drug-Nutrient interactions

​The levodopa + carbidopa, magnesium and vitamin C interaction has only recently gained recognition.  ...

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December 19, 2023

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Aspirin and various nutrients

Drug-Nutrient interactions

Mechanisms and consequences  Interactions between aspirin and various nutrients have been identified over a ...

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December 13, 2023

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Aspirin-folic acid interaction

Drug-Nutrient interactions

​An aspirin-folic acid interaction was a recent “incidental finding” from a pooled analysis of ...

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December 4, 2023

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Aspirin-vitamin C interactions

Drug-Nutrient interactions

​The aspirin-vitamin C interaction was discovered in the early 1970’s.  Mechanisms and consequences  The ...

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November 27, 2023

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Osmolality and prescribed medications

PharmacoNutrition

Mechanisms and consequences  Osmolality seems to be a rarely-considered contributor to a range of ...

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October 16, 2023

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Not to be crushed, chewed, broken or dissolved

PharmacoNutrition

Mechanisms and consequences  Not to be crushed, chewed, broken or dissolved and its many ...

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October 3, 2023

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Excipients (ingredients) and pharmaconutrition

PharmacoNutrition

Mechanisms and consequences  Excipients are the ingredients that comprise about 90% of a medicine ...

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September 18, 2023

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Not clinically relevant

PharmacoNutrition

Mechanisms and consequences  “Not clinically relevant”, “inhibition unlikely at therapeutic interventions”, “clinical inhibition deemed ...

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September 11, 2023

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Altered glycaemia and Vitamin C

PharmacoNutrition

​The side effects of many prescribed medicines include altered glycaemic status which is associated ...

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August 1, 2023

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Multidrug Resistance Proteins (MRPs) and pharmaconutrition

Distribution system

​Multidrug resistance proteins (MRPs) are efflux transporters and as such are responsible for the ...

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July 24, 2023

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Guest case study – hypercalcaemia

PharmacoNutrition

Guest case study  Guest case study - hypercalcaemia is based on a question from ...

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July 10, 2023

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Organic Anion Transporters (OATs) and pharmaconutrition

Distribution system

​OATs (Organic Anion Transporters) are primarily influx transporters albeit some are bidirectional. Mechanisms and consequences  ...

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June 26, 2023

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Organic Anion Transporting Polypeptides (OATPs) and pharmaconutrition

Distribution system

​OATPs (Organic Anion Transporting Proteins) are influx transporters ie transport substrates from blood into ...

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June 12, 2023

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P-glycoprotein and pharmaconutrition

Distribution system

​Permeability-glycoprotein is known as P-glycoprotein or P-gp or multidrug resistance protein (MDR1/2).  Mechanisms and ...

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May 29, 2023

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Sodium Vitamin C Transporters and pharmaconutrition

Distribution system

​The Sodium Vitamin C Transporters (SVCTs) regulate vitamin C homeostasis (system stability) such that ...

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May 22, 2023

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MATE1/2 and pharmaconutrition

Distribution system

Mechanisms and consequences  MATE1/2 (Multi drug and toxin exclusion transporters MATE1 and MATE2) are ...

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May 15, 2023

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BCRP and pharmaconutrition

Distribution system

​BCRP (Breast Cancer Resistance Protein) seems to be an initial defence against environmental insults ...

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May 8, 2023

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Thiamine Transporters 1/2 and pharmaconutrition

Distribution system

Mechanisms and consequences  The thiamine transporters Thiamine Transporter 1 (THTR1) and Thiamine Transporter 2 ...

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May 1, 2023

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Sodium Multivitamin Transporter and pharmaconutrition

Distribution system

​SMVT (Sodium Multivitamin Transporter) facilitates the uptake of biotin, pantothenic acid, lipoic acid, and ...

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April 10, 2023

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Organic Cation Transporters (OCTs) and pharmaconutrition

Distribution system

​OCTs regulate the transfer of many essential organic cations across biological membranes and therefore ...

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April 3, 2023

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Membrane transporters and pharmaconutrition

Distribution system

​Membrane transporters enable substances to cross impermeable cell membranes. Whilst they primarily transfer endogenous ...

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March 27, 2023

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Metformin and pharmaconutrition

PharmacoNutrition

​Metformin’s role in healthcare management is expanding and is now being considered as a ...

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March 13, 2023

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Metformin and vitamin B3

Drug-Nutrient interactions

​The mechanisms by which metformin exerts its effects are not fully understood and current ...

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MedNut Mail is a free fortnightlyish email that consists of either:

  • an editorial - based on some aspect of drug-nutrient or drug-food interactions, and/or
  • a case study - difficult, simple, all real-life (and not identifiable).

Includes examples of how to integrate this information into your clinical assessments.

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MedNut Mail was created in 2021 to provide busy clinicians a simple and convenient format for becoming familiar with interactions between pharmaceuticals and nutrition. Each article is based on recently published research – unless a particular topic has not been addressed for a longer period....

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