PKC (Protein Kinase C) is a second pathway that stimulates insulin-dependent glucose transporters to translocate.Outlined below are the key factors ...
October 21, 2024
October 21, 2024
PKC (Protein Kinase C) is a second pathway that stimulates insulin-dependent glucose transporters to translocate.Outlined below are the key factors ...
September 30, 2024
Glucose transporters and insulin function is rarely considered whilst “insulin and blood sugars” is integral to many care discussions.Given glucose ...
September 10, 2024
Glucose transporters SGLTs (sodium-dependent glucose transporters) are one of the three identified families of glucose transporters in humans.Being a large ...
August 27, 2024
The glucose transporters SWEETs is a relatively recent discovery about which not much is known. The SWEETs are predominantly found ...
August 13, 2024
Glucose transporters (GLUTs) and sodium–glucose linked transporters (SGLTs) are the regulatory pathways essential for glucose homeostasis. Glucose is important as ...
April 23, 2024
Drug-induced tipping points and health management strategies are an unlikely combination and rarely considered. A common definition (https://global-tipping-points.org/what-is-a-tipping-point/) for a ...
December 13, 2023
An aspirin-folic acid interaction was a recent “incidental finding” from a pooled analysis of some studies looking at brain atrophy ...
November 27, 2023
Osmolality seems to be a rarely-considered contributor to a range of primarily gastro-intestinal side effects. It is probably overlooked because ...
October 16, 2023
Not to be crushed, chewed, broken or dissolved and its many variations are commonly included in most Product Information documents. ...
October 3, 2023
Excipients are the ingredients that comprise about 90% of a medicine - they are added to optimise some aspect of ...
September 18, 2023
“Not clinically relevant”, “inhibition unlikely at therapeutic interventions”, “clinical inhibition deemed minimal”, and similar other phrases typically refer to drug-transporter ...
September 11, 2023
The side effects of many prescribed medicines include altered glycaemic status which is associated with physical harm to the body. ...
August 1, 2023
Multidrug resistance proteins (MRPs) are efflux transporters and as such are responsible for the movement of a wide variety of ...
July 10, 2023
OATs (Organic Anion Transporters) are primarily influx transporters albeit some are bidirectional. They can transport a wide variety of anionic ...
June 26, 2023
OATPs (Organic Anion Transporting Proteins) are influx transporters ie transport substrates from blood into organs and cells. OATPs can transport ...
June 12, 2023
Permeability-glycoprotein is known as P-glycoprotein or P-gp or multidrug resistance protein (MDR1/2); it has a large and versatile drug-binding region ...
May 29, 2023
The Sodium Vitamin C Transporters (SVCTs) regulate vitamin C homeostasis (system stability) such that excessive intakes result in reduced intestinal ...
May 22, 2023
MATE1/2 (Multi drug and toxin exclusion transporters MATE1 and MATE2) are major efflux transporters involved in the hepatic and renal ...
May 15, 2023
BCRP (Breast Cancer Resistance Protein) seems to be an initial defence against environmental insults such as phototoxic skin lesions, and ...
May 8, 2023
The thiamine transporters Thiamine Transporter 1 (THTR1) and Thiamine Transporter 2 (THTR2) transfer thiamine and pyridoxine, and are associated with ...